Transcellular openings through frog microvascular endothelium

Neutrophil migration across endothelium: transcellular or paracellular?

matory cytokines downstream of the donor T cell.4 The mechanisms by which T cells are activated during allogeneic transplantation and their subsequent enhancement of host APC allostimulatory capacity will be important avenues for future study. From a clinical perspective, the current study suggests a novel approach to GVHD prophylaxis: the specific deletion of recipient T cells prior to transpl...

Signalling between microvascular endothelium and cardiomyocytes through neuregulin.

Heterocellular communication in the heart is an important mechanism for matching circulatory demands with cardiac structure and function, and neuregulins (Nrgs) play an important role in transducing this signal between the hearts' vasculature and musculature. Here, we review the current knowledge regarding Nrgs, explaining their roles in transducing signals between the heart's microvasculature ...

Network connectivity through small openings

Network connectivity is usually addressed for convex domains where a direct line of sight exists between any two transmitting/receiving nodes. Here, we develop a general theory for the network connectivity properties across a small opening, rendering the domain essentially non-convex. Our analytic approach can go only so far as we encounter what is referred to in statistical physics as quenched...

Morphometric analysis of CNS microvascular endothelium.

The ultrastructural features that are critical to the efficient functioning of the blood-brain barrier (b-bb) were quantified in typical barrier vessels, i.e., cerebral gray and white matter capillaries, and compared with the same parameters in cerebral nonbarrier capillaries (area postrema), and in somatic capillaries, (muscle) of the mouse. The image analysis was done with the help of a simpl...

The isolation and culture of microvascular endothelium.